Carboxymethylcellulose (CMC) is permitted with proper declaration in United States: declare as "carboxymethylcellulose or cellulose gum" in the ingredient list.
Carboxymethylcellulose (cellulose gum, E466) is a plant-cellulose-derived thickener and stabiliser used in ice cream, protein drinks, and gluten-free products. In United States, Carboxymethylcellulose (CMC) is regulated under FDCA & FSMA as a food thickener. FDA GRAS (21 CFR 182.1745). Both names are acceptable in ingredient list. No E-number required.
LabelGuard scans your label for Carboxymethylcellulose (CMC) and all its common names (CMC, Cellulose gum, E466, Sodium carboxymethylcellulose) to verify correct declaration, required E-numbers, and proper functional class labeling under US rules.
Start Your Compliance CheckCarboxymethylcellulose (cellulose gum, E466) is a plant-cellulose-derived thickener and stabiliser used in ice cream, protein drinks, and gluten-free products. It commonly appears in: Ice cream, Salad dressings, Gluten-free bread, Cream cheese, Toothpaste.
EFSA’s re-evaluation found no safety concern and set no ADI. Small recent studies suggesting emulsifiers like CMC may affect the gut microbiome have prompted ongoing research, but no regulator has changed its position; it remains permitted in all major markets.
Declare as "carboxymethylcellulose or cellulose gum" in the ingredient list. FDA GRAS (21 CFR 182.1745). Both names are acceptable in ingredient list. No E-number required.
Carboxymethylcellulose (CMC) may appear under the following names: CMC, Cellulose gum, E466, Sodium carboxymethylcellulose, Sodium CMC. Common hidden sources include: Ice cream, Salad dressings, Gluten-free bread, Cream cheese, Toothpaste, Some beverages.
Carboxymethylcellulose (CMC) is permitted in all major markets with proper declaration.
Last updated: 2026-07-20
Disclaimer: This information is for guidance only and does not constitute legal advice. Always consult official regulations and seek professional legal advice for specific compliance questions.
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